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State Grants

South Carolina Small Business Grants & Funding Programs

South Carolina supports small businesses through statewide commerce and innovation partners, local development agencies, and entrepreneur programs serving coastal, manufacturing, and service-based businesses.

94grants available
From state agencies, SBA & local programs

Statewide Commerce Support

South Carolina businesses can access support aimed at expansion, job creation, and business growth through statewide commerce and development partners.

Innovation and Research Programs

Startup and innovation-led businesses can pursue commercialization support, founder programs, and research-linked initiatives through statewide and regional partners.

Charleston, Columbia, and Regional Support

Charleston, Columbia, Greenville, and other communities offer local business support, corridor programs, and entrepreneur initiatives for eligible firms.

South Carolina Business Grants

94 grants found

open
U.S. Small Business Administration

SBIR/STTR programs

Small Business Innovation Research and Small Business Technology Transfer programs that provide funding for research and development to small businesses.

VariesNationwideRolling
All SectorsInnovation & R&D
open
USDA

USDA Business Programs

USDA’s business programs provide financial backing and technical assistance to stimulate rural business creation and growth.

VariesNationwideRolling
Agriculture & FoodBusiness Support
open
Texas Workforce Commission

Skills for Small Business

The Skills for Small Business grant supports businesses with fewer than 100 employees and incentivizes training for new, full-time workers.

VariesNationwideRolling
All SectorsSkills & Training
open
Empire State Development

NYS-Certified Business Incubator and Innovation Hot Spot Program

Support for early-stage companies varying from physical space to access to capital.

VariesNationwideRolling
All SectorsBusiness Support
open
SBA

Research and Development Grants

Fund a diverse portfolio of startups and small businesses across technology areas and markets to stimulate technological innovation, meet Federal research and development (R&D) needs, and increase commercialization to transition R&D into impact.

VariesNationwideRolling
All SectorsInnovation & R&D
rolling
First Peoples Fund

Yéego Action Grant

The Yéego Action Grant provides quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageInnovation & R&D
open
Wish

The Wish Local Empowerment Program

Assists Black-owned small businesses by dedicating a $2 million fund to support approximately 4,000 Wish Local partners.

$500 - $2,000NationwideInvalid Date
All SectorsBusiness Support
open
StartOut

StartOut Scholarship Program

Offers scholarship opportunities to LGBTQ+ entrepreneurs who wish to participate in their Founder Program and become a Giving Member.

VariesNationwideInvalid Date
All SectorsStartup Support
rolling
PEDIGREE Foundation

PEDIGREE Foundation Disaster Relief Grant

Provides up to $5,000 to nonprofit animal welfare organizations responding to state- or FEMA-declared disasters.

Up to $5,000NationwideInvalid Date
All SectorsCommunity & Social
rolling
NASE

National Association for the Self-Employed (NASE) Growth Grants

The NASE Growth Grants provide up to $4,000 to assist with training, marketing, and more.

$4,000NationwideRolling
All SectorsBusiness Support
upcoming
Founders First CDC

The Kitty Fund

The Kitty Fund will award a total of $20,000 to 20 small business owners who identify as mothers through the Kitty Fund Mompreneur Business Grant.

$20,000Nationwide1 Mar 2026
All SectorsBusiness Support
rolling
IFundWomen

IFundWomen Universal Grant Application

The IFundWomen Universal Grant Application is a resource for female entrepreneurs seeking grants.

VariesNationwideRolling
All SectorsBusiness Support
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Frequently Asked Questions

Common questions about business grants in South Carolina