Massachusetts Small Business Grants & Funding Programs
Massachusetts supports startups, life sciences companies, manufacturers, and neighborhood businesses through statewide innovation programs and local business assistance.
Statewide Growth Programs
Massachusetts businesses can access business growth support, financing, and technical assistance through statewide public and quasi-public partners.
Innovation and Life Sciences Support
Boston and the broader innovation ecosystem provide strong support for technology, biotech, climate, and research-led startups through accelerators and public-private programs.
Local and Corridor Programs
Boston, Worcester, Springfield, and other communities offer local small business grants, corridor support, and entrepreneur assistance for eligible firms.
Massachusetts Business Grants
127 grants found
Life Sciences NIIMBL
Partners with the National Institute for Innovation in Manufacturing Biopharmaceuticals to accelerate biopharma manufacturing innovation and workforce development.
Building Breakthroughs (Biomanufacturing)
Provides grants for capital projects that support biomanufacturing innovation, including upstream/downstream processing and production of cell and gene therapies.
Bits to Bytes
Grant program that funds scientific projects generating and analyzing large datasets to answer pressing life science questions and to train data scientists.
Life Sciences Tax Incentives
Tax incentive program for companies engaged in life sciences research, development, commercialization, and manufacturing in Massachusetts.
Research Infrastructure Program
Provides grants for capital projects that support the life sciences ecosystem in Massachusetts, enabling research and development activities.
SBIR Target Technologies (START) Program
Supports high‑growth companies to expand local employment, promote manufacturing, and stimulate innovation across Massachusetts.
Skills & Pathways
Skills & Pathways is a collection of workforce development programs that provide training, internships, apprenticeships, and mentorship opportunities to help students and adults develop marketable skills and access high‑value careers in Massachusetts.
Innovative Technology Transfer
The Innovative Technology Transfer opportunity includes the MassTech R&D Fund, which supports large‑scale, long‑term research and development infrastructure projects, and MassVentures’ early‑stage venture capital investments that provide seed funding and support for Massachusetts‑based deep‑tech startups.
Key Clusters
Key Clusters offers an annual grant program that supports Regional Tourism Councils in marketing their respective tourism regions across the state.
Small & Growing Businesses
The Small & Growing Businesses section offers a collection of loan, grant, venture capital, and technical assistance programs to support Massachusetts small businesses, administered by MGCC and other state agencies.
Regions & Hubs
The Regional Economic Development Organizations (REDOs) program supports regional projects that grow businesses and the Massachusetts economy, helping attract new employers and strengthen existing businesses.
People & Places
People & Places is a suite of programs that provide funding, tax credits, and technical assistance to support community development, financial literacy, workforce development, and other economic opportunities across Massachusetts.
Frequently Asked Questions
Common questions about business grants in Massachusetts