Regional Grants

Business Grants in Yorkshire & Humber

Yorkshire and the Humber region offers business funding through West Yorkshire and South Yorkshire combined authorities, local councils, and the regional Growth Hub. Key sectors include advanced manufacturing, digital, and healthcare.

220grants available
From councils, growth hubs & national bodies

West Yorkshire Funding

The West Yorkshire Combined Authority runs business support programmes for Leeds, Bradford, and surrounding areas. The AD:VENTURE programme and other schemes support SME growth and innovation.

South Yorkshire Support

South Yorkshire Mayoral Combined Authority provides business grants and support across Sheffield, Rotherham, Doncaster, and Barnsley. Programmes focus on growth, skills, and sector development.

Humber Region Grants

The Humber region including Hull and East Riding has its own business support through local councils and the LEP. Energy and offshore sectors receive particular attention given the region's strategic importance.

Yorkshire & Humber Business Grants

220 grants found

open
Engineering and Physical Sciences Research Council (EPSRC) and Department for Environment, Food and Rural Affairs (Defra)

EPSRC-Defra Reimagining Circularity: full stage

Funding to develop a NetworkPlus that builds new capacity, strengthens community, and enhances research to innovation capabilities focused on the circular economy in data and metrics, or textiles, using the 'Plus' element to accelerate impact.

Up to £5,410,000UK Wide3 Nov 2026
EnvironmentGrants & Funding
upcoming
Engineering and Physical Sciences Research Council (EPSRC), Science and Technology Facilities Council (STFC)

UKRI: Integration of AI/HPC with quantum computing

Apply for funding to expose and overcome critical bottlenecks associated with the implementation of quantum computing within classical computational workflows. This investment will strengthen the UK’s capability to achieve accessible, UK-based quantum computers that deliver benefits beyond classical supercomputers across key sectors of the economy.

Up to £3,750,000UK Wide3 Nov 2026
TechnologyGrants & Funding
open
Innovate UK, on behalf of the Office for Life Sciences (OLS) Cancer Healthcare Goals programme

Advancing innovation in accelerated cancer diagnosis

Funding to support innovative CR&D projects focused on the clinical validation and evaluation of early cancer diagnostic technologies and devices, particularly for less common cancers.

Between £1,500,000 and £4,000,000UK Wide4 Nov 2026
Life Sciences & HealthGrants & Funding
open
Innovate UK, Department for Business, Innovation, Science and Trade (BIST), Advanced Propulsion Centre UK (APC)

DRIVE35 Scale-up Fund drawdown five

UK registered organisations can apply for a share of up to £150 million to create scale up manufacturing facilities for zero emission vehicle technologies. DRIVE35 (Driving Research and Investment in Vehicle Electrification) is a BIST-led programme aimed at transforming the UK’s automotive industry.

Up to £150,000,000UK Wide4 Nov 2026
Transport & AutomotiveGrants & Funding
open
Medical Research Council (MRC)

UKRI translation: MRC proof of concept: stage two

Apply for funding to develop and test novel therapeutics, medical devices, diagnostics and other interventions across any stage of the developmental pathway, from prototype development, through pre-clinical refinement, to early-phase clinical studies (up to phase 2a).

No funding limit (Total fund: £10,000,000)UK Wide4 Nov 2026
Life Sciences & HealthGrants & Funding
open
Innovate UK

FOAK Builder: Programme Entry Expression of Interest

Support to develop a Climate Tech First-of-a-Kind (FOAK) project towards Final Investment Decision (FID). Selected companies receive expert advisory, technical assistance, mentoring, and upskilling support, with potential opportunity to apply for Phase 2 grant funding.

Up to £315,000UK Wide5 Nov 2026
EnvironmentGrants & Funding
open
Innovate UK

Funding opportunity: Expression of interest: First-of-a-Kind (FOAK) builder: programme entry

Expression of interest competition for UK-registered businesses to apply for support to develop a climate tech FOAK commercial project. Successful applicants could be invited to apply for a larger grant through FOAK builder phase two.

Up to £315,000UK Wide5 Nov 2026
EnvironmentGrants & Funding
upcoming
Economic and Social Research Council (ESRC)

Economic Statistics Centre of Excellence 2027-2030 – invite only

Supports the Economic Statistics Centre of Excellence (ESCoE) to conduct high-quality research that improves economic measurement, enhances key statistics production, modernises data collection, and assists the ONS in shaping global economic measurement standards.

Up to £8,007,500UK Wide5 Nov 2026
FinanceGrants & Funding
open
Medical Research Council (MRC)

Invite only: Precision prevention: biological mechanisms of response variation

Apply for funding to investigate why biomedical prevention interventions work differently across people. Projects must generate mechanistic evidence in humans by testing biomedical experimental interventions or challenges in pre-disease or early disease states, providing insight into how to improve the targeting and effectiveness of precision prevention strategies.

Up to £5,000,000UK Wide5 Nov 2026
Life Sciences & HealthGrants & Funding
open
Natural Environment Research Council (NERC)

Large Grant full applications: November 2026 (invite only)

Funding to support innovative, large-scale and complex projects that tackle big science questions and have the potential to produce world-leading research.

Between £1,120,000 and £3,450,000UK Wide5 Nov 2026
EnvironmentGrants & Funding
open
Energy Systems Catapult

Energy Resilience Accelerator – helping SMEs scale their resilience innovations

A programme designed to connect ambitious SMEs with industry partners (Centrica, NHS England, NESO, NGED, SSEN) to collaboratively develop trial proposals tackling pressing energy resilience challenges, with fully funded technical and business support and potential trial funding.

Up to £40,000UK Wide8 Nov 2026
Clean EnergyGrants & Funding
open
UK Research and Innovation

Transformative sustainable AI technologies

Apply for funding for projects focused on speculative and high-risk research with the potential to deliver high rewards and a step change in the sustainability of future AI systems. Projects should consider technological innovations across the AI stack.

Up to £602,500UK Wide10 Nov 2026
AI & Data ScienceGrants & Funding
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Frequently Asked Questions

Common questions about business grants in Yorkshire & Humber